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- Limited financial resources required for addressing the tremendous needs of end-users in Member States, using technically and developmentally sound nuclear technologies;
- Wide variation in AFRA Member States’ stages of development in nuclear science and technology, which requires intensive efforts to narrow down the gap and to create conducive environment for regional cooperation;
- Inadequate qualified and skilled human resources in many Member States, which limits the outreach of AFRA projects;
- Improvement required in management and leadership styles at all levels of the management of the AFRA programme;
- Inadequate succession plans and knowledge preservation strategies, resulting in lengthy replacement of staff leaving the national nuclear institutions in Member States;
- Poor status of the basic nuclear infrastructure in some AFRA countries, which requires significant upgrading before it can be utilized efficiently through AFRA activities.